MDC1 anticorps

N° du produit ABIN7264389

L’anticorps anti-MDC1 Polyclonal produit chez le Lapin a été validé pour IHC et IF. Il convient pour la détection de MDC1 dans des échantillons provenant de Humain. }

Aperçu rapide pour MDC1 anticorps (ABIN7264389)

Antigène: MDC1 (Mdc1 (MDC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MDC1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MDC1 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human MDC1 (NP_055456.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur MDC1

Antigène: MDC1 (Mdc1 (MDC1))

Autre désignation: MDC1

Sujet: The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.

ID gène: 9656

UniProt: Q14676