PRKCA beta 2 anticorps (pThr638, pThr641)

N° du produit ABIN7265128

Détail du produit anti-PRKCA beta 2 anticorps

Antigène: PRKCA beta 2 (Protein Kinase C alpha beta 2 (PRKCA beta 2))

Épitope: pThr638, pThr641

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKCA beta 2 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Phosphorylated antibody

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding T641 of human PRKCB

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:100 IF 1:100-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PRKCA beta 2

Antigène: PRKCA beta 2 (Protein Kinase C alpha beta 2 (PRKCA beta 2))

Autre désignation: PKCalpha/beta II (PRKCA beta 2 Produits)

Sujet: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

ID gène: 5578, 5579

UniProt: P17252, P05771