Serotonin Receptor 1A anticorps (3rd Intracellular Loop)

N° du produit ABIN7043615

L’anticorps anti-Serotonin Receptor 1A Polyclonal Lapin est utilisé pour la détection de Serotonin Receptor 1A dans des échantillons de Rat. Il a été validé pour WB, IHC et IF.

Aperçu rapide pour Serotonin Receptor 1A anticorps (3rd Intracellular Loop) (ABIN7043615)

Antigène: Serotonin Receptor 1A (HTR1A)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Serotonin Receptor 1A anticorps

Épitope: 3rd Intracellular Loop, AA 251-266

Fonction: A Rabbit Polyclonal Antibody to 5-Hydroxytryptamine Receptor 1A

Réactivité croisée: Souris, Rat

Réactivité croisée (Details): Will not recognize human 5-hydroxytryptamine receptor 1A.

Homologie: Mouse - identical

Attributs du produit: Anti-5HT1A Receptor (HTR1A) Antibody is directed against an intracellular epitope of the rat 5-Hydroxytryptamine receptor 1A. Anti-5HT1A Receptor (HTR1A) Antibody (ABIN7043615, ABIN7045278 and ABIN7045279) can be used for western blot and immunohistochemistry applications. It has been designed to recognize 5HT1A receptor from rat and mouse samples.

Purification: Affinity purified on immobilized antigen.

Immunogène: KKSLNGQPGSGDWRRC, corresponding to amino acid residues 251-266 of rat 5-Hydroxytryptamine receptor 1A

Isotype: IgG

Information d'application

Indications d'application:

WB: 1:200

FC: The optimal concentration should be determined by the user

ICC: The optimal concentration should be determined by the user

IHC: 1:100

IP: The optimal concentration should be determined by the user

Commentaires:

Cited Application: IP

Negative Control: (ABIN7236780)

Blocking Peptide: (ABIN7236780)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Concentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Détails sur Serotonin Receptor 1A

Antigène: Serotonin Receptor 1A (HTR1A)

Autre désignation: HTR1A

Sujet:

Synonyms: 5-Hydroxytryptamine receptor 1A, Serotonin receptor 1A

Description: Serotonin (5-hydroxytryptamine, 5-HT1) is an important neurotransmitter in the central nervous system (CNS) that exerts its neuronal activity via 5-HT receptors.5-HT receptors are subdivided into seven families termed 5-HT1 through 5-HT7.1 The 5-HT receptor families belong to the G-protein coupled receptor superfamily with the exception of 5-HT3 receptor class which belongs to the ligand-gated ion channels.2The 5-HT1 receptor class comprises of five different receptors (5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E and 5-HT1F) which share 41-63 % overall sequence identity and couple preferentially to Gi/Go to inhibit cAMP formation.2The 5-HT1A receptor is the most widespread of all the 5-HT receptors. In the CNS, 5-HT1A receptors exist in the cerebral cortex, hippocampus, septum, amygdala and raphe nucelus in high densities, and was also demonstrated in a variety of tissues from various species.2,3 Activation of 5-HT1A receptor decreases blood pressure and heart rate, and is involved in learning, memory, relieving anxiety and depression.1,4

ID gène: 24473

NCBI Accession: NM_000524

UniProt: P19327

Pathways: Signalistation JAK/STAT, Synaptic Membrane, Feeding Behaviour