Recombinant CD28 anticorps
Aperçu rapide pour Recombinant CD28 anticorps (ABIN7072234)
Antigène
Voir toutes CD28 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-CD28 [JJ316], Mouse IgG1, kappa
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Specificité
- Recognises rat CD28 and can trigger T-cell proliferation in vitro and in vivo.
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Attributs du produit
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Original Species of Ab: Mouse
Original Format of Ab: IgG1
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Purification
- Protein A affinity purified
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Immunogène
- Made by immunizing BALB/c mice with rat CD28 cDNA-transfected A20/J cells.
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Isotype
- IgG1 kappa
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anti-CD28 (CD28) (AA 1-120) antibody
CD28 Reactivité: Humain, Souris, Rat FACS, WB, ELISA, IHC (fro), IF (p), IHC (p), IF (cc) Hôte: Lapin Polyclonal unconjugated
anti-CD28 (CD28) antibodyCD28 Reactivité: Humain, Non-Human Primate FACS, WB, IP, IHC (fro), ICC Hôte: Souris Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) antibody (FITC)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 FITC
anti-CD28 (CD28) antibodyCD28 Reactivité: Humain, Non-Human Primate FACS, WB, IP, Func, IHC (fro), ICC Hôte: Souris Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) (AA 19-152) antibodyCD28 Reactivité: Humain FACS, ELISA Hôte: Lapin Monoclonal DM61 unconjugated Recombinant Antibody
anti-CD28 (CD28) antibodyCD28 Reactivité: Rat FACS, IP Hôte: Souris Monoclonal JJ319 unconjugated
anti-CD28 (CD28) antibody (PE)CD28 Reactivité: Rat FACS Hôte: Souris Monoclonal JJ319 PE
anti-CD28 (CD28) antibody (PerCP)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 PerCP
anti-CD28 (CD28) antibody (PE)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 PE
anti-CD28 (CD28) antibody (APC)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 APC
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Indications d'application
- This antibody binds rat CD28 and can convey as a co-stimulatory signal. At 100-1000-fold higher concentration than required for co-stimulation JJ316 (unlike the clone JJ319 marketed by competitors (see Tacke et al. 1997)) can induce proliferation of all T-cell subsets without TCR engagement.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD28
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Autre désignation
- CD28
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Sujet
- TP44, T-cell-specific surface glycoprotein CD28
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UniProt
- P31042
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Antigène
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