Recombinant CD28 anticorps

N° du produit ABIN7072235

L’anticorps Lapin Chimeric anti-CD28 a été validé pour FACS, IF, IHC, CoSt et Agon. Il convient pour détecter CD28 dans des échantillons de Rat.

Aperçu rapide pour Recombinant CD28 anticorps (ABIN7072235)

Antigène: CD28

Type d'anticorp: Recombinant Antibody

Reactivité: Rat

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CD28 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Co-Stimulation (CoSt), Agonist (Agon)

Clone: JJ316

Détail du produit anti-CD28 anticorps

Fonction: Anti-CD28 [JJ316], Rabbit IgG, kappa

Specificité: Recognises rat CD28 and can trigger T-cell proliferation in vitro and in vivo.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: Made by immunizing BALB/c mice with rat CD28 cDNA-transfected A20/J cells.

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody binds rat CD28 and can convey as a co-stimulatory signal. At 100-1000-fold higher concentration than required for co-stimulation JJ316 (unlike the clone JJ319 marketed by competitors (see Tacke et al. 1997)) can induce proliferation of all T-cell subsets without TCR engagement.

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD28

Antigène: CD28

Autre désignation: CD28

Sujet: TP44, T-cell-specific surface glycoprotein CD28

UniProt: P31042

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response