Recombinant CD28 anticorps

N° du produit ABIN7072237

Cet anticorps Lapin Chimeric détecte spécifiquement CD28 dans FACS, IHC, SPR, CoSt et Agon. Il présente une réactivité envers Souris.

Aperçu rapide pour Recombinant CD28 anticorps (ABIN7072237)

Antigène: CD28

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CD28 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Surface Plasmon Resonance (SPR), Co-Stimulation (CoSt), Agonist (Agon)

Clone: D665

Détail du produit anti-CD28 anticorps

Fonction: Anti-CD28 [D665], Rabbit IgG, kappa

Specificité: This antibody binds to the laterally exposed C'D loop of CD28 and induces T cell proliferation without TCR ligation.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: The original D665 antibody was generated by immunizing mice alternately with A20 cells expressing mCD28 i.p. and with recombinant mCD28Ig s.c.

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody binds to mouse CD28. The original mouse IgG1 version was shown to trigger T-cell proliferation in vitro and in vivo in a TCR-independent manner and is a superagonistic antibody. This antibody does not compete with E18 (Ab00286).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD28

Antigène: CD28

Autre désignation: CD28

Sujet: TP44, T-cell-specific surface glycoprotein CD28, TP44

UniProt: P31041

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response