Recombinant FOLR2 anticorps

N° du produit ABIN7072338

Cet anticorps anti-FOLR2 est un anticorps Rat Monoclonal détectant FOLR2 dans WB et IHC. Adapté pour Souris.

Aperçu rapide pour Recombinant FOLR2 anticorps (ABIN7072338)

Antigène: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp FOLR2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: CL10

Détail du produit anti-FOLR2 anticorps

Fonction: Anti-Folate receptor beta [CL10], Rat IgG2a, kappa

Attributs du produit:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogène: FRbeta -transfected RBL2H3 cells.

Isotype: IgG2a kappa

Information d'application

Indications d'application: The antibody binds specifically to FRβ, a member of the folate receptor family. The receptor binds with high affinity to folic acid and folic acid derivatives, and transports 5-methyltetrahydrofolate into the cell. The receptor is expressed on the surface of tumour associated macrophages (TAMs) that promote growth and metastasis of tumours such as gliomas and colon, breast and lung carcinomas. Research has shown FRβ is only expressed on activated macrophages, and thereby a monoclonal antibody that targets the receptor can be useful in the diagnosis of the cancer. Furthermore, the antibody may be conjugated with a toxin, delivering the drug only to TAMs and not to healthy macrophages.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur FOLR2

Antigène: FOLR2 (Folate Receptor 2 (Fetal) (FOLR2))

Autre désignation: Folate receptor beta

Sujet: FRβ, Folate receptor 2, Folate-binding protein 2.

UniProt: Q05685

Pathways: Dicarboxylic Acid Transport