Recombinant CD36 anticorps

N° du produit ABIN7072627

Cet anticorps Lapin Chimeric détecte spécifiquement CD36 dans FACS, IHC, IF, IP et BP. Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant CD36 anticorps (ABIN7072627)

Antigène: CD36

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CD36 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Blocking Peptide (BP)

Clone: 185-1G2 (B467)

Détail du produit anti-CD36 anticorps

Fonction: Anti-CD36 [185-1G2 (B467)], Rabbit IgG, kappa

Specificité: This antibody is specific against CD36. The antibody recognises an epitope between amino acids 155 - 183. CD36 is a receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. It acts as a receptor for hepatitis C virus in hepatocytes and appears to facilitate its cell entry as well as mediates uptake of M. fortuitum, E. coli and S. aureus.

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: IgM

Purification: Protein A affinity purified

Immunogène: This antibody was raised by immunizing mice with stimulated human leukocytes.

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody is recommended for the detection and analysis of CD36 via various methods. For instance, it was used to stain ovarian cancer tissue samples via immunohistochemistry, demonstrating that CD36 was expressed in the cytoplasm of cancer cells while stromal cells were negative (Têtu et al., 2008). Furthermore, 185-1G2 antibody was shown to precipitate CD36 from a platelate lysate sample (Miao et al., 2001). Finally, this antibody has also blocking properties against CD36 and has been widely used to inhibit this receptor (Short et al., 2005).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgM format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD36

Antigène: CD36

Autre désignation: CD36

Sujet: SRB1, Scavenger receptor class B member 1, CD36 and LIMPII analogous 1, CLA-1, CD36 antigen-like 1, Collagen type I receptor, thrombospondin receptor-like 1, SR-BI

UniProt: Q8WTV0

Pathways: Signalisation TLR, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins