FBXW4 anticorps

N° du produit ABIN7073903

Détail du produit anti-FBXW4 anticorps

Antigène: FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXW4 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse FBXW4

Information d'application

Indications d'application: WB (M,R) 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur FBXW4

Antigène: FBXW4 (F-Box and WD Repeat Domain Containing 4 (FBXW4))

Autre désignation: FBXW4 (FBXW4 Produits)

Synonymes: anticorps dac, anticorps hag, anticorps hagoromo, anticorps wu:fk63g06, anticorps FBXW4, anticorps DAC, anticorps FBW4, anticorps FBWD4, anticorps SHFM3, anticorps SHSF3, anticorps Dac, anticorps Fbw4, anticorps dactylin, anticorps dactylyn, anticorps F-box and WD repeat domain containing 4, anticorps F-box and WD-40 domain protein 4, anticorps fbxw4, anticorps FBXW4, anticorps Fbxw4

Sujet: F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins, and they are a family of eukaryotic proteins characterized by an approximately 40 amino acid motif. SCF complex, a class of ubiquitin ligases, consists of invariable components, Skp1 and Cullin, and variable components of F-box proteins, which have a primary role in determining substrate specificity. FBXW4, also known as SHFM3, encodes F-box and WD-40 domain-containing protein 4. Defects in SHFM3 are a cause of split-hand/foot malformation type 3 (SHFM3), an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.

Poids moléculaire: 46 kDa

ID gène: 30838

NCBI Accession: NP_038935

UniProt: Q9JMJ2