LRP2 anticorps
Aperçu rapide pour LRP2 anticorps (ABIN7074514)
Antigène
Voir toutes LRP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat
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Purification
- Affinity purification
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Immunogène
- Recombinant protein corresponding to Mouse Lrp2 / Megalin
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Indications d'application
- IHC/IF (M,R) 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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- LRP2 (Low Density Lipoprotein Receptor-Related Protein 2 (LRP2))
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Autre désignation
- Lrp2/Megalin
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Sujet
- The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones.
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ID gène
- 14725
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NCBI Accession
- NP_001074557
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UniProt
- A2ARV4
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Pathways
- Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport
Antigène
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