CHRNB1 anticorps

N° du produit ABIN7074841

Détail du produit anti-CHRNB1 anticorps

Antigène: CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNB1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse Nicotinic Acetylcholine Receptor beta/CHRNB1

Information d'application

Indications d'application: IHC/IF (M,R) 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur CHRNB1

Antigène: CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

Autre désignation: Nicotinic Acetylcholine Receptor beta/CHRNB1 (CHRNB1 Produits)

Synonymes: anticorps CHRNB1, anticorps ACHRB, anticorps CHRNB, anticorps CMS1D, anticorps CMS2A, anticorps SCCMS, anticorps Acrb, anticorps RNACRB1, anticorps Achr-2, anticorps cholinergic receptor nicotinic beta 1 subunit, anticorps cholinergic receptor, nicotinic, beta 1 (muscle), anticorps acetylcholine receptor beta subunit, anticorps cholinergic receptor, nicotinic, beta polypeptide 1 (muscle), anticorps CHRNB1, anticorps chrnb1, anticorps ACHRB, anticorps Chrnb1

Sujet: Acetylcholine receptors (AChRs) are integral membrane proteins that respond to the binding of acetylcholine (ACh), a neurotransmitter synthesized, stored and finally released by cholinergic neurons. After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one each of the beta, delta, and gamma (in immature muscle) or epsilon (in mature muscle) subunits. CHRNB1 gene encodes acetylcholine receptor subunit beta (ACHRB). Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

ID gène: 11443

NCBI Accession: NP_033731

UniProt: P09690

Pathways: Synaptic Membrane