SOCS7 anticorps

N° du produit ABIN7075765

Détail du produit anti-SOCS7 anticorps

Antigène: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS7 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse SOCS7

Information d'application

Indications d'application: IHC/IF (R) 1:650-1:1300/1:400-1:1200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur SOCS7

Antigène: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Autre désignation: SOCS7 (SOCS7 Produits)

Synonymes: anticorps NAP4, anticorps NCKAP4, anticorps SOCS4, anticorps SOCS6, anticorps 2310063P06Rik, anticorps C85125, anticorps Nap4, anticorps GB13951, anticorps zgc:175115, anticorps SOCS7, anticorps socs7, anticorps suppressor of cytokine signaling 7, anticorps suppressor of cytokine signaling, anticorps SOCS7, anticorps Socs7, anticorps LOC413772, anticorps socs7

Sujet: SOCS7 regulates signaling cascades probably through protein ubiquitination and/or sequestration. SOCS7 functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. SOCS7 inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.

ID gène: 192157

NCBI Accession: NP_619598

UniProt: Q8VHQ2