CD28 anticorps (APC)
Aperçu rapide pour CD28 anticorps (APC) (ABIN7076481)
Antigène
Voir toutes CD28 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
Clone
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Fonction
- CD28 APC Antibody
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Attributs du produit
- The clone C-B281, a mouse monoclonal antibody selectively recognizes a 44 kDa type I cell surface glycoprotein known as CD28. It is expressed by all T cells and acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, B7-1 (CD80) and B7-2 (CD86), which are primarily expressed by the activated B cells as well as other antigen-presenting cells. CD28-CD28 ligands signaling induces TCR functional activation resulting T cell proliferation, production of higher levels of IL-2 and enhancing T cell cytotoxicity.
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Purification
- Purified
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Pureté
- >95 %
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Immunogène
- Recombinant human CD28 protein
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Isotype
- IgG1, kappa
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Indications d'application
- FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- 2-8°C, Conjugated antibodies should never be frozen.
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- CD28
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Autre désignation
- CD28
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ID gène
- 940
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UniProt
- P10747
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Antigène
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