Cullin 2 anticorps (AA 365-745) (HRP)

N° du produit ABIN705275

L’anticorps Lapin Polyclonal anti-Cullin 2 a été validé pour ELISA, IHC (p) et IHC (fro). Il convient pour détecter Cullin 2 dans des échantillons de Humain.

Aperçu rapide pour Cullin 2 anticorps (AA 365-745) (HRP) (ABIN705275)

Antigène: Cullin 2 (CUL2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cullin 2 est conjugé à/à la HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Cullin 2 anticorps (HRP)

Épitope: AA 365-745

Homologie: Human,Mouse,Rat,Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Cullin 2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Cullin 2

Antigène: Cullin 2 (CUL2)

Autre désignation: Cullin 2

Sujet:

Synonyms: Cullin2, Cullin-2, CUL 2, MGC131970, CUL2_HUMAN.

Background: Cullin 2 is a member of the family of human Cullin genes (CUL1, 2, 3, 4a, 4b and 5) homologous to the S. cerevisiae cdc53 gene. It is a component of E3 ubiquitin ligase complexes, including the inactive transcriptional elongation complex SIII, which mediates the ubiquitination of hypoxia-inducible factor (HIF). SIII is formed by three subunits: Elongin C, Elongin B and VHL. Cullin 2 may serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.

ID gène: 8453

Pathways: M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome