BAX anticorps (AA 1-192)
Aperçu rapide pour BAX anticorps (AA 1-192) (ABIN7111961)
Antigène
Voir toutes BAX AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-192
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Fonction
- BAX antibody
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Purification
- Protein A+G purification
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
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Immunogen sequence: 1-192aa
Immunogen: BCL2-associated X protein
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Isotype
- IgG2a
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Indications d'application
- WB: 1:1000-1:10000, IHC: 1:400-1:1000, IF: 1:50-1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- BAX (BCL2-Associated X Protein (BAX))
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Autre désignation
- BAX
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Sujet
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Synonyms: Apoptosis regulator BAX|Bcl-2-like protein 4 (Bcl2-L-4)|BAX|BCL2L4
Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
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Poids moléculaire
- 21 kDa
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ID gène
- 581
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UniProt
- Q07812
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Pathways
- Signalisation p53, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Antigène
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