FAM20C anticorps

N° du produit ABIN7114089

Détail du produit anti-FAM20C anticorps

Antigène: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM20C est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: family with sequence similarity 20, member C

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur FAM20C

Antigène: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Autre désignation: FAM20C (FAM20C Produits)

Synonymes: anticorps DMP-4, anticorps DMP4, anticorps GEF-CK, anticorps RNS, anticorps C76981, anticorps mKIAA4081, anticorps RGD1311980, anticorps si:ch73-266a4.1, anticorps FAM20C, golgi associated secretory pathway kinase, anticorps family with sequence similarity 20, member C, anticorps family with sequence similarity 20, member Cb, anticorps FAM20C, anticorps Fam20c, anticorps fam20cb

Sujet: Synonyms:Dentin matrix protein 4, DMP 4, DMP4, FAM20C, Protein FAM20C, RNS Background:Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth(PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome(PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity(PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1(PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion(PubMed:26091039).

Poids moléculaire: 50 kDa

ID gène: 56975

UniProt: Q8IXL6