GCK anticorps

N° du produit ABIN7114576

Cet anticorps Lapin Polyclonal détecte spécifiquement GCK dans WB, ELISA et IP. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour GCK anticorps (ABIN7114576)

Antigène: GCK (Glucokinase (Hexokinase 4) (GCK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GCK est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-GCK anticorps

Fonction: GCK antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: glucokinase(hexokinase 4)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur GCK

Antigène: GCK (Glucokinase (Hexokinase 4) (GCK))

Autre désignation: GCK

Sujet:

Synonyms: Hexokinase-4 (HK4)|Glucokinase|Hexokinase type IV (HK IV)|Hexokinase-D|GCK

Background: Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.

Poids moléculaire: 50-52 kDa

ID gène: 2645

UniProt: P35557

Pathways: Signalisation MAPK, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process