IDS anticorps

N° du produit ABIN7115175

Détail du produit anti-IDS anticorps

Antigène: IDS (Iduronate 2-Sulfatase (IDS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IDS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: iduronate 2-sulfatase

Clone: 2D2

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur IDS

Antigène: IDS (Iduronate 2-Sulfatase (IDS))

Autre désignation: Iduronate 2 sulfatase (IDS Produits)

Synonymes: anticorps mps2, anticorps sids, anticorps zgc:158245, anticorps MPS2, anticorps SIDS, anticorps AW214631, anticorps iduronate 2-sulfatase, anticorps IDS, anticorps CpipJ_CPIJ004938, anticorps ids, anticorps Ids

Sujet: Synonyms:IDS, iduronate 2 sulfatase, Idursulfase Background:Iduronate 2-sulfatase (IDS) is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations causing IDS deficiency in humans result in the lysosomal storage of these glycosaminoglycans and Hunter syndrome, an X chromosome-linked disease. IDS is synthesized as two precursor forms of 76 and 90 kDa that are converted, through a 62 kDa intermediate, to 55 and 45 kDa mature polypeptides due to an internal proteolytic cleavage (PMID: 10838181).

Poids moléculaire: 76 kDa, 55 kDa

ID gène: 3423

UniProt: P22304

Pathways: Glycosaminoglycan Metabolic Process