PRKAA2 anticorps (AA 340-552)

N° du produit ABIN7117965

Cet anticorps anti-PRKAA2 est un anticorps Lapin Polyclonal détectant PRKAA2 dans WB, ELISA, IHC, IF et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour PRKAA2 anticorps (AA 340-552) (ABIN7117965)

Antigène: PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKAA2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-PRKAA2 anticorps

Épitope: AA 340-552

Fonction: PRKAA2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 340-552aa

Immunogen: protein kinase, AMP-activated, alpha 2 catalytic subunit

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000-1:10000, IHC: 1:20-1:200, IF: 1:10-1:100, IP:1:500-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur PRKAA2

Antigène: PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))

Autre désignation: PRKAA2

Sujet:

Synonyms: 5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2)|Acetyl-CoA carboxylase kinase (ACACA kinase)|Hydroxymethylglutaryl-CoA reductase kinase (HMGCR kinase)|PRKAA2|AMPK|AMPK2

Background: PRKAA2(protein kinase, AMP-activated, alpha 2 catalytic subunit), also named as AMPKA2, AMPK, PRKAA, AMPK2, belonogs to the CAMK Ser/Thr protein kinase family and SNF1 subfamily. PRKAA2 is an αβγ heterotrimer that is activated by low cellular energy status, such as decreases in both the ATP/AMP ratio and the phosphocreatine content and it is a glycogen synthase kinase, phosphorylating Ser7 at the NH2 terminus, which decreases glycogen synthase activity(PMID:14532170). The protein can be ubiquitinated(PMID:21224036).

Poids moléculaire: 62 kDa

ID gène: 5563

UniProt: P54646

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, L'effet Warburg