RAB43 anticorps

N° du produit ABIN7118226

Cet anticorps anti-RAB43 est un anticorps Lapin Polyclonal détectant RAB43 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour RAB43 anticorps (ABIN7118226)

Antigène: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB43 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RAB43 anticorps

Fonction: RAB43 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: RAB43, member RAS oncogene family

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RAB43

Antigène: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Autre désignation: RAB43

Sujet:

Synonyms: Ras-related protein Rab-43|Ras-related protein Rab-41|RAB43|RAB41

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Poids moléculaire: 23 kDa

ID gène: 339122

UniProt: Q86YS6