RASGRF1 anticorps

N° du produit ABIN7118317

Cet anticorps Lapin Polyclonal détecte spécifiquement RASGRF1 dans IHC, ELISA, WB et IF. Il présente une réactivité envers Souris et Humain.

Aperçu rapide pour RASGRF1 anticorps (ABIN7118317)

Antigène: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Reactivité: Souris, Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASGRF1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-RASGRF1 anticorps

Fonction: RASGRF1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: Ras protein-specific guanine nucleotide-releasing factor 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur RASGRF1

Antigène: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Autre désignation: RASGRF1

Sujet:

Synonyms: Ras-specific guanine nucleotide-releasing factor 1 (Ras-GRF1)|Guanine nucleotide-releasing protein (GNRP)|Ras-specific nucleotide exchange factor CDC25|RASGRF1|CDC25|GNRP|GRF1

Background: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Poids moléculaire: 145 kDa

ID gène: 5923

UniProt: Q13972

Pathways: Signalisation RTK, Cycle Cellulaire, M Phase