ARHGEF7 anticorps

N° du produit ABIN7118495

L’anticorps Lapin Polyclonal anti-ARHGEF7 a été validé pour WB, ELISA et IP. Il convient pour détecter ARHGEF7 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour ARHGEF7 anticorps (ABIN7118495)

Antigène: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-ARHGEF7 anticorps

Fonction: ARHGEF7 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: Rho guanine nucleotide exchange factor(GEF) 7

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000-1:4000, IP: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ARHGEF7

Antigène: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Autre désignation: ARHGEF7

Sujet:

Synonyms: Rho guanine nucleotide exchange factor 7|Beta-Pix|COOL-1|PAK-interacting exchange factor beta|p85|ARHGEF7|COOL1|KIAA0142|P85SPR|PAK3BP|PIXB

Background: Acts as a RAC1 guanine nucleotide exchange factor(GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions(By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.

Poids moléculaire: 70 kDa

ID gène: 8874

UniProt: Q14155

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation