SQSTM1 anticorps (AA 1-440)

N° du produit ABIN7118890

Cet anticorps Souris Monoclonal détecte spécifiquement SQSTM1 dans WB, IHC, IF et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour SQSTM1 anticorps (AA 1-440) (ABIN7118890)

Antigène: SQSTM1 (Sequestosome 1 (SQSTM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SQSTM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Clone: 5H3

Détail du produit anti-SQSTM1 anticorps

Épitope: AA 1-440

Fonction: SQSTM1 antibody

Purification: protein A+G purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 1-440aa

Immunogen: sequestosome 1

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:1000 - 1:4000, IHC: 1:50 - 1:500, IF: 1:20 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SQSTM1

Antigène: SQSTM1 (Sequestosome 1 (SQSTM1))

Autre désignation: SQSTM1

Sujet:

Synonyms: Sequestosome-1|EBI3-associated protein of 60 kDa (EBIAP, p60)|Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa|Ubiquitin-binding protein p62|SQSTM1|ORCA|OSIL

Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Poids moléculaire: 62 kDa

ID gène: 8878

UniProt: Q13501

Pathways: Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy