SOCS6 anticorps

N° du produit ABIN7119606

Cet anticorps anti-SOCS6 est un anticorps Lapin Polyclonal détectant SOCS6 dans WB, IHC et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SOCS6 anticorps (ABIN7119606)

Antigène: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-SOCS6 anticorps

Fonction: SOCS6 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: suppressor of cytokine signaling 6

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SOCS6

Antigène: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Autre désignation: SOCS6

Sujet:

Synonyms: Suppressor of cytokine signaling 6 (SOCS-6)|Cytokine-inducible SH2 protein 4 (CIS-4)|Suppressor of cytokine signaling 4 (SOCS-4)|SOCS6|CIS4|SOCS4

Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS(Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins(By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.

Poids moléculaire: 70 kDa

ID gène: 9306

UniProt: O14544

Pathways: Signalistation JAK/STAT, Carbohydrate Homeostasis