SMARCD1 anticorps

N° du produit ABIN7119638

Détail du produit anti-SMARCD1 anticorps

Antigène: SMARCD1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 1 (SMARCD1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SMARCD1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1

Clone: 1A7

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur SMARCD1

Antigène: SMARCD1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily D, Member 1 (SMARCD1))

Autre désignation: SMARCD1 (SMARCD1 Produits)

Synonymes: anticorps rsc6p, anticorps baf60a, anticorps cracd1, anticorps MGC69403, anticorps BAF60A, anticorps CRACD1, anticorps Rsc6p, anticorps wu:fa10h07, anticorps wu:fb82d01, anticorps wu:fi45f10, anticorps AA407987, anticorps Baf60a, anticorps D15Kz1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 L homeolog, anticorps SMARCD1, anticorps smarcd1, anticorps smarcd1.L, anticorps Smarcd1

Sujet: Synonyms:BAF60A Background:Involved in chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex(npBAF complex) and the neuron-specific chromatin remodeling complex(nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes(nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth(By similarity). Has a strong influence on vitamin D-mediated transcriptional activity from an enhancer vitamin D receptor element(VDRE). May be a link between mammalian SWI-SNF-like chromatin remodeling complexes and the vitamin D receptor(VDR) heterodimer. Mediates critical interactions between nuclear receptors and the BRG1/SMARCA4 chromatin-remodeling complex for transactivation.

Poids moléculaire: 58 kDa

ID gène: 6602

UniProt: Q96GM5