anticorps TAF1C, anticorps Tafi95, anticorps mTAFI95, anticorps MGC:39976, anticorps SL1, anticorps TAFI110, anticorps TAFI95, anticorps TATA-box binding protein associated factor, RNA polymerase I subunit C, anticorps TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa, anticorps TATA-box binding protein associated factor, RNA polymerase I, C, anticorps TATA-box binding protein associated factor, RNA polymerase 1 subunit C, anticorps TAF1C, anticorps Taf1c
Sujet
Synonyms: Background:Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.