THO Complex 2 anticorps

N° du produit ABIN7119925

Détail du produit anti-THO Complex 2 anticorps

Antigène: THO Complex 2 (THOC2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp THO Complex 2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: THO complex 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:200-1:1000, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur THO Complex 2

Antigène: THO Complex 2 (THOC2)

Autre désignation: THOC2 (THOC2 Produits)

Synonymes: anticorps RGD1561623, anticorps THO, anticorps Tho2, anticorps fb73e08, anticorps fd21d11, anticorps wu:fb73e08, anticorps wu:fd21d11, anticorps si:bz1o18.2, anticorps CXorf3, anticorps THO2, anticorps dJ506G2.1, anticorps hTREX120, anticorps 6330441O12Rik, anticorps D130005M13Rik, anticorps Gm1139, anticorps Gm1793, anticorps THO complex 2, anticorps Thoc2, anticorps THOC2, anticorps thoc2

Sujet: Synonyms:CXorf3 Background:Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex(EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus(KSHV) intronless mRNAs and infectious virus production. THOC2(and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains. Required for NXF1 localization to the nuclear rim. Plays a role for proper neuronal development.

Poids moléculaire: 150 kDa

ID gène: 57187

UniProt: Q8NI27