USP44 anticorps

N° du produit ABIN7120522

Détail du produit anti-USP44 anticorps

Antigène: USP44 (Ubiquitin Specific Peptidase 44 (USP44))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP44 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: ubiquitin specific peptidase 44

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur USP44

Antigène: USP44 (Ubiquitin Specific Peptidase 44 (USP44))

Autre désignation: USP44 (USP44 Produits)

Synonymes: anticorps usp44, anticorps USP49, anticorps E430004F17Rik, anticorps zgc:55661, anticorps ubiquitin specific peptidase 44, anticorps ubiquitin specific peptidase 44 L homeolog, anticorps ubiquitin specific peptidase 44 S homeolog, anticorps USP44, anticorps usp44.L, anticorps usp44.S, anticorps usp44, anticorps Usp44

Sujet: Synonyms:Deubiquitinating enzyme 44, DKFZp434D0127, FLJ14528, Ubiquitin thiolesterase 44, USP44 Background:Deubiquitinase that plays a key regulatory role in the spindle assembly checkpoint or mitotic checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome(APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex(also named mitotic checkpoint complex), thereby preventing premature activation of the APC/C. Promotes association of MAD2L1 with CDC20 and reinforces the spindle assembly checkpoint. Acts as a negative regulator of histone H2B(H2BK120ub1) ubiquitination.

Poids moléculaire: 81 kDa

ID gène: 84101

UniProt: Q9H0E7

Pathways: M Phase