WEE2 anticorps

N° du produit ABIN7120837

Détail du produit anti-WEE2 anticorps

Antigène: WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WEE2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: WEE1 homolog 2(S. pombe)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur WEE2

Antigène: WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))

Autre désignation: WEE2 (WEE2 Produits)

Synonymes: anticorps Xe-wee1, anticorps wee1, anticorps wee1-b, anticorps wee1a, anticorps wee1b, anticorps wee2-b, anticorps xwee1, anticorps xwee2, anticorps WEE1B, anticorps Gm1065, anticorps Wee1B, anticorps WEE2, anticorps im:5913035, anticorps si:ch211-238n5.5, anticorps wu:fi13b10, anticorps zgc:123074, anticorps WEE1 homolog 2, anticorps WEE1 homolog 2 (S. pombe), anticorps wee2, anticorps WEE2, anticorps Wee2

Sujet: Synonyms:FLJ16107, WEE1 homolog 2(S. pombe), Wee1 like protein kinase 1B, Wee1 like protein kinase 2, WEE1B, Wee1B kinase, WEE2 Background:Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle(GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation(By similarity).

Poids moléculaire: 63 kDa

ID gène: 494551

UniProt: P0C1S8

Pathways: M Phase