Recombinant Angiotensin I Converting Enzyme 1 anticorps (AA 652-788)

N° du produit ABIN7126290

L’anticorps anti-Angiotensin I Converting Enzyme 1 Monoclonal Lapin est utilisé pour la détection de Angiotensin I Converting Enzyme 1 dans des échantillons de Humain. Il a été validé pour ELISA.

Aperçu rapide pour Recombinant Angiotensin I Converting Enzyme 1 anticorps (AA 652-788) (ABIN7126290)

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Angiotensin I Converting Enzyme 1 est non-conjugé

Application: ELISA

Clone: ACE-7004R

Détail du produit anti-Angiotensin I Converting Enzyme 1 anticorps

Épitope: AA 652-788

Fonction: Recombinant Angiotensin I Converting Enzyme (ACE) / CD143 Antibody

Specificité: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

Réactivité croisée (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 652-788) of human ACE/CD143 protein

Isotype: IgG, kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), ,Optimal dilution for a specific application should be determined.

Positive_Control: Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Angiotensin I Converting Enzyme 1

Antigène: Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))

Autre désignation: ACE

Sujet:

ACE, ACE1, angiotensin 1 converting enzyme 1, carboxycathepsin, CD143, CD143 antigen, DCP, DCP1, dipeptidyl carboxypeptidase 1, Kininase II, MVCD3, peptidase P, testicular ECA

gastrointestinal system and prostate., Heart, Kidney, Ubiquitously expressed, with highest levels in lung

Poids moléculaire: 150kDa

ID gène: 1636, 298469

UniProt: P12821

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration