APOB anticorps (AA 592-689)
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- Antigène Voir toutes APOB Anticorps
- APOB (Apolipoprotein B (APOB))
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Épitope
- AA 592-689
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp APOB est non-conjugé
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Application
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificité
- Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated byAPOBEC1 (also designated human (or rat) small intestinal apolipoprotein BmRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steadystate proportion of edited and unedited RNA molecules. Two forms of apoBare known to circulate in the plasma of mammals. ApoB-100 is a proteinprimarily synthesized in the liver as a structural component of very low densitylipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesizedin the small intestine and contains the amino-terminal 2,152 amino acids ofthe larger protein. This organ-specific partitioning of apoB production is theresultof RNA editing of a common apoB gene.
- Réactivité croisée (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Human recombinant APOB protein fragment (around aa592-689) (exact sequence is proprietary)
- Isotype
- IgG2b
- Top Product
- Discover our top product APOB Anticorps primaire
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- Indications d'application
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human liver or kidney tissue.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- APOB (Apolipoprotein B (APOB))
- Autre désignation
- APOB (APOB Produits)
- Synonymes
- anticorps FLDB, anticorps LDLCQ4, anticorps Ac1-060, anticorps Apo B-100, anticorps ApoB-100, anticorps ApoB-48, anticorps AI315052, anticorps apob-100, anticorps apob-48, anticorps APOB-100, anticorps ApoB(100), anticorps APOB, anticorps apolipoprotein B, anticorps APOB, anticorps Apob
- Sujet
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ApoB 100, ApoB 48, Apolipoprotein B (including Ag(x) antigen), Apolipoprotein B 100, Apolipoprotein B 48, Apolipoprotein B, FLDB, LDLCQ4,Apolipoprotein B /APOB
Cellular localisation: Cytoplasm. Secreted. - Poids moléculaire
- 512kDa
- ID gène
- 338, 120759
- UniProt
- P04114
- Pathways
- Lipid Metabolism
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