Recombinant GZMB anticorps

N° du produit ABIN7127523

L’anticorps Lapin Monoclonal anti-GZMB a été validé pour IHC, ELISA et IF. Il convient pour détecter GZMB dans des échantillons de Humain.

Aperçu rapide pour Recombinant GZMB anticorps (ABIN7127523)

Antigène: GZMB (Granzyme B (GZMB))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: 6A1

Détail du produit anti-GZMB anticorps

Fonction: GZMB Recombinant Monoclonal Antibody

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human Granzyme B

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:200, IF:1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: GZMB

Sujet:

Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Aliases: Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E), GZMB, CGL1 CSPB CTLA1 GRB

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis