Recombinant NUP153 anticorps
Aperçu rapide pour Recombinant NUP153 anticorps (ABIN7127649)
Antigène
Voir toutes NUP153 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée
- Humain
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Purification
- Affinity-chromatography
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Immunogène
- A synthesized peptide derived from human Nup153
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Isotype
- IgG
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Indications d'application
- Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- NUP153 (Nucleoporin 153kDa (NUP153))
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Autre désignation
- NUP153
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Sujet
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Background: Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus, in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element (CTE) in a NXF1- and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex (NPC).
Aliases: Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153), NUP153
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UniProt
- P49790
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Pathways
- Protein targeting to Nucleus
Antigène
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