PGC anticorps

N° du produit ABIN7130598

Détail du produit anti-PGC anticorps

Antigène: PGC (Pepsinogen C (PGC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGC est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen affinity purification

Immunogène: Fusion protein of Human PGC

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PGC

Antigène: PGC (Pepsinogen C (PGC))

Autre désignation: PGC (PGC Produits)

Synonymes: anticorps PEPC, anticorps PGII, anticorps 2210410L06Rik, anticorps Upg-1, anticorps Upg1, anticorps CPGC, anticorps gastricsin, anticorps PG1, anticorps Pg-1, anticorps PGNC, anticorps PGC, anticorps Gastricsin, anticorps progastricsin (pepsinogen C), anticorps progastricsin, anticorps PGC, anticorps Pgc

Sujet:

Background: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.

Aliases: Gastricsin antibody, PEPC antibody, PEPC_HUMAN antibody, pepsin C antibody, Pepsinogen C antibody, pepsinogen group II antibody, PGC antibody, PGII antibody, preprogastricsin antibody, Progastricsin antibody

UniProt: P20142