Cofilin anticorps

N° du produit ABIN7137920

Cet anticorps Lapin Polyclonal détecte spécifiquement Cofilin dans WB, IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour Cofilin anticorps (ABIN7137920)

Antigène: Cofilin (CFL1) (Cofilin 1 (CFL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cofilin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Cofilin anticorps

Fonction: CFL1 (Ab-3) Antibody

Réactivité croisée: Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogène: Peptide sequence around aa. 1~5 (M-A-S-G-V) derived from Human cofilin.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Cofilin

Antigène: Cofilin (CFL1) (Cofilin 1 (CFL1))

Autre désignation: CFL1

Sujet:

Background: Controls reversibly actin polymerization and depolymerization in a pH -sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

Kobayashi M, et al. (2006) EMBO J 25(4): 713-26.
Wang Y, et al. (2005)Biol Chem 280(13): 12683-9.
Smith-Beckerman DM, et al. (2005) Mol Cell Proteomics: 156-68.

Aliases: 18 kDa phosphoprotein antibody, CFL 1 antibody, CFL antibody, CFL1 antibody, COF1_HUMAN antibody, Cofilin 1 antibody, Cofilin 1 non muscle antibody, Cofilin antibody, Cofilin non muscle isoform antibody, Cofilin-1 antibody, epididymis secretory protein Li 15 antibody, HEL-S-15 antibody, non-muscle isoform antibody, p18 antibody

UniProt: P23528

Pathways: Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events