PDPK1 anticorps (pSer241)

N° du produit ABIN7138502

Cet anticorps Lapin Polyclonal détecte spécifiquement PDPK1 dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PDPK1 anticorps (pSer241) (ABIN7138502)

Antigène: PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDPK1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-PDPK1 anticorps

Épitope: pSer241

Fonction: Phospho-PDPK1 (Ser241) Antibody

Réactivité croisée: Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of serine 241 (A-N-S(p)-F-V) derived from Human PDK1.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PDPK1

Antigène: PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))

Autre désignation: PDPK1

Sujet:

Background: Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development.

Scheid MP,et al. (2005)Mol Cell Biol, 25(6): 2347-63
Chen H, et al. (2001) Biochemistry, 40(39): 11851-9
Sato S,et al. (2002) J Biol Chem, 277(42): 39360-7
Lim MA, et al.(2003)Proc Natl Acad Sci U S A, 100(24): 14006-11

Aliases: 3 phosphoinositide dependent protein kinase 1 antibody, 3-phosphoinositide-dependent protein kinase 1 antibody, hPDK 1 antibody, hPDK1 antibody, MGC20087 antibody, MGC35290 antibody, OTTHUMP00000159109 antibody, OTTHUMP00000159110 antibody, OTTHUMP00000174525 antibody, PDK1 antibody, Pdpk1 antibody, PDPK1_HUMAN antibody, PDPK2 antibody, PDPK2P antibody, PkB kinase antibody, PkB kinase like gene 1 antibody, PkB like 1 antibody, PRO0461 antibody, Protein kinase antibody

UniProt: O15530

Pathways: Signalisation PI3K-Akt, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals