HDAC8 anticorps (pSer39)

N° du produit ABIN7138593

Détail du produit anti-HDAC8 anticorps

Antigène: HDAC8 (Histone Deacetylase 8 (HDAC8))

Épitope: pSer39

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC8 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain, Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of serine 39 (R-A-S(p)-M-V) derived from Human HDAC8.

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:100, IF:1:100-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur HDAC8

Antigène: HDAC8 (Histone Deacetylase 8 (HDAC8))

Autre désignation: HDAC8 (HDAC8 Produits)

Synonymes: anticorps HD8, anticorps CDLS5, anticorps HDACL1, anticorps MRXS6, anticorps RPD3, anticorps WTS, anticorps 2610007D20Rik, anticorps RGD1562895, anticorps wu:fd19a02, anticorps zgc:66196, anticorps ATHDA8, anticorps HDA8, anticorps HISTONE DEACETYLASE 8, anticorps T27G7.14, anticorps T27G7_14, anticorps histone deacetylase 8, anticorps histone deacetylase 8, anticorps histone deacetylase 8 L homeolog, anticorps CC1G_05302, anticorps hdac8, anticorps HDAC8, anticorps Hdac8, anticorps hdac8.L, anticorps HDA08

Sujet:

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Lee H, et al. (2004) Mol Cell Biol. 24(2): 765-773.

Aliases: CDA07 antibody, CDLS5 antibody, HD 8 antibody, HD8 antibody, HDAC 8 antibody, Hdac8 antibody, HDAC8_HUMAN antibody, HDACL 1 antibody, HDACL1 antibody, Histone deacetylase 8 antibody, Histone deacetylase like 1 antibody, MRXS6 antibody, RPD 3 antibody, RPD3 antibody, WTS antibody

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process