NFKBIB anticorps (pThr19)

N° du produit ABIN7138792

Cet anticorps anti-NFKBIB est un anticorps Lapin Polyclonal détectant NFKBIB dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour NFKBIB anticorps (pThr19) (ABIN7138792)

Antigène: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFKBIB est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NFKBIB anticorps

Épitope: pThr19

Fonction: Phospho-NFKBIB (Thr19) Antibody

Réactivité croisée: Souris

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of Threonine 19(C-D-S(p)-G-L) derived from Human IkappaB- beta.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NFKBIB

Antigène: NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

Autre désignation: NFKBIB

Sujet:

Background: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Aliases: I kappa B beta antibody, I-kappa-B-beta antibody, IkappaBbeta antibody, IKB beta antibody, IkB-B antibody, IkB-beta antibody, IKBB antibody, IKBB_HUMAN antibody, IkBbeta antibody, NF kappa BIB antibody, NF-kappa-B inhibitor beta antibody, NF-kappa-BIB antibody, Nfkbib antibody, Thyroid receptor interacting protein 9 antibody, Thyroid receptor-interacting protein 9 antibody, TR interacting protein 9 antibody, TR-interacting protein 9 antibody, TRIP-9 antibody, TRIP9 antibody

UniProt: Q15653

Pathways: Signalisation NF-kappaB, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades