Phospholipase C gamma 2 anticorps (pTyr753)

N° du produit ABIN7139060

Cet anticorps Lapin Polyclonal détecte spécifiquement Phospholipase C gamma 2 dans WB, ELISA et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour Phospholipase C gamma 2 anticorps (pTyr753) (ABIN7139060)

Antigène: Phospholipase C gamma 2 (PLCG2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Phospholipase C gamma 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-Phospholipase C gamma 2 anticorps

Épitope: pTyr753

Fonction: Phospho-PLCG2 (Tyr753) Antibody

Réactivité croisée: Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 753 (S-L-Y(p)-D-V) derived from Human PLCg2.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Phospholipase C gamma 2

Antigène: Phospholipase C gamma 2 (PLCG2)

Autre désignation: PLCG2

Sujet:

Background: The production of the second messenger molecules diacylglycerol. (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

Kim YJ, et al. (2004) Mol Cell Biol 24: 9986-9999
Humphries LA, et al. (2004) J Biol Chem 279 : 37651-37661
Suzuki-Inoue K, et al. (2004) Biochem J 378 : 1023-1029
Rodriguez R, et al. (2003) Biochem J 374 : 269-280

Aliases: 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 2 antibody, 1-phosphatidylinositol-4 antibody, 5-bisphosphate phosphodiesterase gamma-2 antibody, EC 3.1.4.11 antibody, Phosphoinositide phospholipase C antibody, Phosphoinositide phospholipase C-gamma-2 antibody, Phospholipase C gamma 2 antibody, Phospholipase C, gamma 2 (phosphatidylinositol specific) antibody, Phospholipase C-gamma-2 antibody, Phospholipase C-IV antibody, PLC 2 antibody, PLC gamma 2 antibody, PLC IV antibody, PLC-gamma-2 antibody, PLC-IV antibody, Plcg2 antibody, PLCG2_HUMAN antibody

UniProt: P16885

Pathways: Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling