GRK2 anticorps (C-Term)

N° du produit ABIN7140291

L’anticorps anti-GRK2 Monoclonal Souris est utilisé pour la détection de GRK2 dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour GRK2 anticorps (C-Term) (ABIN7140291)

Antigène: GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GRK2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GRK2 anticorps

Épitope: C-Term

Fonction: ADRBK1 Monoclonal Antibody

Réactivité croisée: Chien, Souris, Porc, Rat

Purification: Affinity purified

Immunogène: Purified recombinant human ADRBK1(C-term.) protein fragments expressed in E.coli.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: buffer containing 0.1M Tris-Glycine ( pH 7.4, 150 mM NaCl) with 0.2 % sodium azide, 50 %,glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GRK2

Antigène: GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))

Autre désignation: ADRBK1

Sujet:

Background: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1.

Aliases: GRK2, BARK1, BETA-ARK1

UniProt: P25098

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling