MICAL2 anticorps (AA 1-495) (FITC)

N° du produit ABIN7141996

Détail du produit anti-MICAL2 anticorps (FITC)

Antigène: MICAL2 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2))

Épitope: AA 1-495

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MICAL2 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human [F-actin]-monooxygenase MICAL2 protein (1-495AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MICAL2

Antigène: MICAL2 (Microtubule Associated Monoxygenase, Calponin and LIM Domain Containing 2 (MICAL2))

Autre désignation: MICAL2 (MICAL2 Produits)

Synonymes: anticorps MICAL-2, anticorps MICAL2PV1, anticorps MICAL2PV2, anticorps 5330438E18Rik, anticorps 9530064J02, anticorps mKIAA0750, anticorps RGD1311773, anticorps microtubule associated monooxygenase, calponin and LIM domain containing 2, anticorps MICAL2, anticorps Mical2

Sujet:

Background: Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin and regulates the SRF signaling. Acts by modifying nuclear actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization. Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA.

Aliases: MICAL2 antibody, KIAA0750 antibody, MICAL2PV1 antibody, MICAL2PV2 antibody, [F-actin]-monooxygenase MICAL2 antibody, EC 1.14.13.225 antibody, Molecule interacting with CasL protein 2 antibody, MICAL-2 antibody

UniProt: O94851