AKAP1 anticorps (AA 413-662)

N° du produit ABIN7142902

Détail du produit anti-AKAP1 anticorps

Antigène: AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))

Épitope: AA 413-662

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human A-kinase anchor protein 10, mitochondrial protein (413-662AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur AKAP1

Antigène: AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))

Autre désignation: AKAP1 (AKAP1 Produits)

Synonymes: anticorps AKAP1, anticorps akap1, anticorps fa08b04, anticorps wu:fa08b04, anticorps AKAP, anticorps AKAP121, anticorps AKAP149, anticorps AKAP84, anticorps D-AKAP1, anticorps PPP1R43, anticorps PRKA1, anticorps SAKAP84, anticorps TDRD17, anticorps Akap, anticorps C76494, anticorps C81186, anticorps DAKAP1, anticorps S-AKAP84, anticorps Akap84, anticorps A-kinase anchoring protein 1, anticorps A kinase (PRKA) anchor protein 1b, anticorps A kinase (PRKA) anchor protein 1, anticorps AKAP1, anticorps akap1b, anticorps akap1, anticorps Akap1

Sujet:

Background: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity).

Aliases: AKAP10A-kinase anchor protein 10 antibody, mitochondrial antibody, AKAP-10 antibody, Dual specificity A kinase-anchoring protein 2 antibody, D-AKAP-2 antibody, Protein kinase A-anchoring protein 10 antibody, PRKA10 antibody

UniProt: O43572

Pathways: Synaptic Membrane