Kir2.2 anticorps (AA 182-433) (Biotin)

N° du produit ABIN7145026

Détail du produit anti-Kir2.2 anticorps (Biotin)

Antigène: Kir2.2 (KCNJ12) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12))

Épitope: AA 182-433

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kir2.2 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human ATP-sensitive inward rectifier potassium channel 12 protein (182-433aa)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Kir2.2

Antigène: Kir2.2 (KCNJ12) (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 12 (KCNJ12))

Autre désignation: KCNJ12 (KCNJ12 Produits)

Synonymes: anticorps IRK-2, anticorps IRK2, anticorps KCNJN1, anticorps Kir2.2, anticorps Kir2.2v, anticorps hIRK, anticorps hIRK1, anticorps hkir2.2x, anticorps kcnj12x, anticorps Kir2.1, anticorps IRK, anticorps KIR2.2, anticorps MB-IRK2, anticorps potassium voltage-gated channel subfamily J member 12, anticorps ATP-sensitive inward rectifier potassium channel 12, anticorps potassium inwardly-rectifying channel, subfamily J, member 12, anticorps KCNJ12, anticorps LOC746628, anticorps Kcnj12

Sujet:

Background: Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Aliases: ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12), KCNJ12, IRK2 KCNJN1

UniProt: Q14500