KCNMB1 anticorps (AA 40-130) (Biotin)

N° du produit ABIN7146339

Détail du produit anti-KCNMB1 anticorps (Biotin)

Antigène: KCNMB1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1))

Épitope: AA 40-130

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNMB1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Calcium-activated potassium channel subunit beta-1 protein (40-130AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur KCNMB1

Antigène: KCNMB1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 1 (KCNMB1))

Autre désignation: KCNMB1 (KCNMB1 Produits)

Synonymes: anticorps KCNMB1, anticorps BKbeta1, anticorps K(VCA)beta, anticorps SLO-BETA, anticorps hbeta1, anticorps hslo-beta, anticorps k(VCA)beta-1, anticorps slo-beta-1, anticorps BKBETA, anticorps potassium calcium-activated channel subfamily M regulatory beta subunit 1, anticorps potassium large conductance calcium-activated channel, subfamily M, beta member 1, anticorps KCNMB1, anticorps Kcnmb1

Sujet:

Background: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Increases the apparent Ca(2+)/voltage sensitivity of the KCNMA1 channel. It also modifies KCNMA1 channel kinetics and alters its pharmacological properties. It slows down the activation and the deactivation kinetics of the channel. Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1. Its presence is also a requirement for internal binding of the KCNMA1 channel opener dehydrosoyasaponin I (DHS-1) triterpene glycoside and for external binding of the agonist hormone 17-beta-estradiol (E2). Increases the binding activity of charybdotoxin (CTX) toxin to KCNMA1 peptide blocker by increasing the CTX association rate and decreasing the dissociation rate.

Aliases: BK channel beta subunit antibody, BK channel subunit beta 1 antibody, BK channel subunit beta-1 antibody, BKbeta antibody, BKbeta1 antibody, Calcium activated potassium channel subfamily M subunit beta 1 antibody, Calcium activated potassium channel subunit beta 1 antibody, Calcium activated potassium channel subunit beta antibody, Calcium-activated potassium channel antibody, Calcium-activated potassium channel subunit beta antibody, Calcium-activated potassium channel subunit beta-1 antibody, Charybdotoxin receptor subunit beta 1 antibody, Charybdotoxin receptor subunit beta-1 antibody, Hbeta1 antibody, hslo beta antibody, K(VCA)beta 1 antibody, K(VCA)beta antibody, K(VCA)beta-1 antibody, KCMB1_HUMAN antibody, KCNMB 1 antibody, Kcnmb1 antibody, Large conductance Ca2+ activated K+ channel beta 1 subunit antibody, Maxi K channel beta subunit antibody, Maxi K channel subunit beta 1 antibody, Maxi K channel subunit beta-1 antibody, Potassium large conductance calcium activated channel subfamily M beta member 1 antibody, Slo beta 1 antibody, SLO beta antibody, Slo-beta antibody, Slo-beta-1 antibody, subfamily M subunit beta-1 antibody

UniProt: Q16558