FLIP anticorps (AA 1-250)
Aperçu rapide pour FLIP anticorps (AA 1-250) (ABIN7146901)
Antigène
Voir toutes FLIP (CFLAR) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-250
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Réactivité croisée
- Humain
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Purification
- >95%, Protein G purified
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Immunogène
- Recombinant Human CASP8 and FADD-like apoptosis regulator protein (1-250AA)
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Isotype
- IgG
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Indications d'application
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:20-1:200,
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
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Autre désignation
- CFLAR
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Sujet
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Background: Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
Aliases: c FLIP antibody, c FLIPL antibody, c FLIPR antibody, c FLIPS antibody, c-FLIP antibody, c-FLIPL antibody, c-FLIPR antibody, c-FLIPS antibody, CASH antibody, CASP8 and FADD like apoptosis regulator antibody, CASP8 and FADD-like apoptosis regulator subunit p12 antibody, CASP8AP1 antibody, Caspase homolog antibody, Caspase like apoptosis regulatory protein antibody, Caspase related inducer of apoptosis antibody, Caspase-eight-related protein antibody, Caspase-like apoptosis regulatory protein antibody, Casper antibody, cellular flice inhibitory protein antibody, Cellular FLICE-like inhibitory protein antibody, CFLA antibody, Cflar antibody, CFLAR_HUMAN antibody, CLARP antibody, FADD like anti apoptotic molecule antibody, FADD-like antiapoptotic molecule 1 antibody, FLAME antibody, FLAME-1 antibody, FLAME1 antibody, FLIP antibody, I FLICE antibody, I-FLICE antibody, Inhibitor of FLICE antibody, MACH-related inducer of toxicity antibody, MRIT antibody, OTTHUMP00000163715 antibody, OTTHUMP00000206475 antibody, OTTHUMP00000206476 antibody, OTTHUMP00000206478 antibody, OTTHUMP00000206479 antibody, OTTHUMP00000206480 antibody, OTTHUMP00000206482 antibody, OTTHUMP00000207360 antibody, Usurpin antibody, Usurpin beta antibody
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UniProt
- O15519
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Pathways
- Apoptose, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Antigène
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