MAPKAP Kinase 2 anticorps (pSer272) (Cy5)

N° du produit ABIN710535

Cet anticorps anti-MAPKAP Kinase 2 Polyclonal Lapin conjugué à Cy5 (ABIN710535) détecte spécifiquement MAPKAP Kinase 2 dans WB et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MAPKAP Kinase 2 anticorps (pSer272) (Cy5) (ABIN710535)

Antigène: MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPKAP Kinase 2 est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-MAPKAP Kinase 2 anticorps (Cy5)

Épitope: pSer272

Fonction: Phospho-MAPKAPK2 (Ser272) Polyclonal Antibody, Cy5 Conjugated

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human MAPKAPK2 around the phosphorylation site of Ser272

Isotype: IgG

Information d'application

Indications d'application: WB(1:300-5000), IF(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur MAPKAP Kinase 2

Antigène: MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))

Autre désignation: MAPKAPK2

Sujet:

Synonyms: MAPKAPK2phospho S272,P-MAPKAPK2Ser272, MAP Kinase Activated Protein Kinase 2, MAPK activated protein kinase 2, MAPKAP kinase 2, MAPKAPK 2, MAPKAPK2, Mitogen Activated Protein Kinase Activated Protein Kinase 2, MAPK2_HUMAN, MK 2, MK2, MAPKAPK-2.

Background: MAP kinase activated protein kinase 2 (MAPKAP Kinase 2), also known as p45 hsp27 kinase, is a 45-54 kDa serine/threonine protein kinase that contains a proline rich sequence and two putative SH3 binding sites. MAPKAP Kinase 2 is activated in response to stress, IL1 and TNF, possibly catalyzed by p38/Hog dependent phosphorylation. One of the major substrates of MAPKAP Kinase 2 is hsp27, which stimulates actin polymerization in order to facilitate recovery from destruction of cytoskeleton during cellular stresses. MAPKAP2 is implicated in several disorders including ischemic brain injury and heart failure and has been shown to be important in regulating stress resistance and the production of TNF alpha.

Poids moléculaire: 44kDa

ID gène: 9261

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades