COPS8 anticorps (AA 150-198) (Biotin)

N° du produit ABIN7148508

L’anticorps Lapin Polyclonal anti-COPS8 a été validé pour ELISA. Il convient pour détecter COPS8 dans des échantillons de Humain.

Aperçu rapide pour COPS8 anticorps (AA 150-198) (Biotin) (ABIN7148508)

Antigène: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COPS8 est conjugé à/à la Biotin

Application: ELISA

Détail du produit anti-COPS8 anticorps (Biotin)

Épitope: AA 150-198

Fonction: COPS8 Antibody, Biotin conjugated

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human COP9 signalosome complex subunit 8 protein (150-198AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur COPS8

Antigène: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Autre désignation: COPS8

Sujet:

Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

Aliases: COP9 homolog antibody, COP9 signalosome complex subunit 8 antibody, COP9 signalosome subunit 8 antibody, Cops8 antibody, CSN8 antibody, CSN8_HUMAN antibody, hCOP9 antibody, JAB1 containing signalosome subunit 8 antibody, JAB1-containing signalosome subunit 8 antibody, SGN8 antibody, Signalosome subunit 8 antibody

UniProt: Q99627

Pathways: Cycle Cellulaire