Cullin 2 anticorps (AA 591-742)

N° du produit ABIN7148749

Cet anticorps anti-Cullin 2 est un anticorps Lapin Polyclonal détectant Cullin 2 dans WB, ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour Cullin 2 anticorps (AA 591-742) (ABIN7148749)

Antigène: Cullin 2 (CUL2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cullin 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Cullin 2 anticorps

Épitope: AA 591-742

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Cullin-2 protein (591-742AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Cullin 2

Antigène: Cullin 2 (CUL2)

Autre désignation: CUL2

Sujet:

Background: Core component of multiple cullin-RING-based ECS (ElonginB/C-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of target proteins. May serve as a rigid scaffold in the complex and may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1 (By similarity). The functional specificity of the ECS complex depends on the substrate recognition component. ECS(VHL) mediates the ubiquitination of hypoxia-inducible factor (HIF).

Aliases: Cul2 antibody, CUL 2 antibody, CUL-2 antibody, CUL2 antibody, CUL2_HUMAN antibody, cullin 2 antibody, cullin homolog 2 antibody, Cullin-2 antibody, MGC131970 antibody

UniProt: Q13617

Pathways: M Phase, Asymmetric Protein Localization, SARS-CoV-2 Protein Interactome