AFT7 anticorps (AA 1-117)

N° du produit ABIN7148809

Détail du produit anti-AFT7 anticorps

Antigène: AFT7 (Activating Transcription Factor 7 (AFT7))

Épitope: AA 1-117

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AFT7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Cyclic AMP-dependent transcription factor ATF-7 protein (1-117AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur AFT7

Antigène: AFT7 (Activating Transcription Factor 7 (AFT7))

Autre désignation: ATF7 (AFT7 Produits)

Synonymes: anticorps ATFA, anticorps 1110012F10Rik, anticorps 9430065F09Rik, anticorps AI549878, anticorps C130020M04Rik, anticorps ATF7, anticorps fa97a09, anticorps fc25b12, anticorps wu:fa97a09, anticorps wu:fc25b12, anticorps atfa, anticorps activating transcription factor 7, anticorps activating transcription factor 7b, anticorps ATF7, anticorps Atf7, anticorps atf7b, anticorps atf7

Sujet:

Background: Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5\\\'-GTGACGT[AG][AG]-3\\\'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family. Isoform 4/ATF-A0 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter. Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.

Aliases: 1110012F10Rik antibody, 9430065F09Rik antibody, Activating transcription factor 7 antibody, AI549878 antibody, ATF7 antibody, Atf7 protein antibody, ATF7_HUMAN antibody, ATFA antibody, C130020M04Rik antibody, cAMP-dependent transcription factor ATF-7 antibody, Cyclic AMP-dependent transcription factor ATF 7 antibody, Cyclic AMP-dependent transcription factor ATF-7 antibody, MGC31554 antibody, MGC57182 antibody, Transcription factor ATF A antibody, Transcription factor ATF-A antibody

UniProt: P17544