Cyclin C anticorps (AA 240-283)

N° du produit ABIN7148838

L’anticorps Lapin Polyclonal anti-Cyclin C a été validé pour WB, ELISA, IHC et IF. Il convient pour détecter Cyclin C dans des échantillons de Humain.

Aperçu rapide pour Cyclin C anticorps (AA 240-283) (ABIN7148838)

Antigène: Cyclin C (CCNC)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin C est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Cyclin C anticorps

Épitope: AA 240-283

Fonction: CCNC Antibody

Réactivité croisée: Souris

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human Cyclin-C protein (240-283AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Cyclin C

Antigène: Cyclin C (CCNC)

Autre désignation: CCNC

Sujet:

Background: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.

Aliases: ccnc antibody, CCNC_HUMAN antibody, CycC antibody, Cyclin C antibody, Cyclin-C antibody, hSRB11 antibody, OTTHUMP00000016897 antibody, SRB11 homolog antibody

UniProt: P24863

Pathways: Cycle Cellulaire, Regulation of Lipid Metabolism by PPARalpha